AICAR 50mg

Within Europe this product is supplied including bacteriostatic water; outside Europe only the compound vial is provided.

For research use only — not for human or veterinary use.

Product Overview

AICAR (5-Aminoimidazole-4-carboxamide ribonucleotide) is a synthetic research compound widely studied in laboratory environments for its role in cellular energy sensing, metabolic signalling and AMP-activated protein kinase (AMPK) pathway modelling. This lyophilized 50 mg preparation is supplied in a 10 ml vial and intended exclusively for controlled in vitro research applications.

Compound Overview

AICAR is an adenosine analogue that has been used in biochemical research since the late twentieth century as a reference compound for studying intracellular energy balance and metabolic stress signalling. In laboratory models, AICAR is utilised to explore AMPK-associated signalling cascades, energy-regulation mechanisms and downstream metabolic pathway interactions.

Due to its well-characterised molecular structure and reproducible behaviour under controlled conditions, AICAR has become a standard research compound in metabolic and bioenergetic studies.

Historical Background and Scientific Context

Research into cellular energy regulation accelerated during the 1980s and 1990s as scientists identified key signalling molecules involved in metabolic homeostasis. AICAR emerged as a valuable experimental compound for investigating AMP-mimetic signalling behaviour and AMPK pathway activation models. It continues to be employed in preclinical and in vitro research frameworks exploring metabolic regulation and cellular energy dynamics.

Mechanistic Focus in Research

• AMPK-associated signalling pathway modelling
• Cellular energy sensing and metabolic regulation research
• Metabolic stress-response pathway investigation
• Comparative structure–function evaluation of AMP analogues
• Controlled in vitro biochemical and metabolic studies

Analytical and Manufacturing Notes

This AICAR preparation is supplied as a lyophilized powder and is engineered to exceed 99 percent purity based on controlled synthesis and internal quality benchmarks. Independent third-party analytical verification may be provided separately when available.

Research Applications

• Metabolic pathway and energy-regulation research
• AMPK signalling and activation studies
• Cellular bioenergetics modelling
• Comparative metabolic compound evaluation
• Controlled in vitro biochemical investigations

Grail Formula Quality

Grail Formula research compounds are produced using controlled synthesis protocols and stringent internal quality standards. Each product is engineered for high purity, consistency and reproducibility to support reliable laboratory research outcomes.

When You Choose Grail Formula…

Researchers receive carefully prepared research materials supplied in sealed vials with batch identification and documented handling procedures. EU shipments include bacteriostatic water; outside the EU only the compound vial is supplied.

Used solely for in vitro experiments and cannot be:

• Used in clinical trials involving humans
• Administered to humans as part of an experiment or investigation
• Supplied to another party for human investigational use

Engineered to exceed 99 percent purity
Lyophilized AICAR supplied in a 10 ml vial
High-purity research-grade metabolic compound
Designed for AMPK and metabolic pathway research
Produced under controlled synthesis conditions
EU shipments include bacteriostatic water
For research use only — not for human or veterinary use

For laboratory research only. Not intended for human consumption, injection, or cosmetic use.

This product is for research purposes only. Not for human use or diagnostic/therapeutic applications. Keep out of reach of children.