PT‑141 10mg

For research use only — not for human or veterinary use.

Analytical Verification (COA)

Each batch of PT-141 supplied by Grail Formula undergoes independent third-party laboratory verification to confirm compound identity, assay content, purity and microbiological safety.

Analytical testing for this batch was performed by Liquilabs s.r.o. (Czechia) using validated chromatographic and spectrometric techniques.

Batch: GF082025028

Key analytical results include:

• Assay Content: 11.88 mg
• Identification – Retention Time: 0.992
• Identification – Spectrum: 997
• Purity: approximately 99 percent
• Bacterial Endotoxins: 0.0120 EU per mg
• Total Aerobic Microbial Count: not detected
• Total Yeast and Mold Count: not detected

Independent heavy metal screening confirmed no detectable levels of arsenic, cadmium, cobalt, lead, nickel, mercury or vanadium.

These analytical procedures ensure traceability, purity verification and laboratory-grade compound consistency.

Product Overview

PT-141, also known as Bremelanotide, is a synthetic peptide research compound frequently studied in controlled laboratory environments examining melanocortin receptor signalling and neuroendocrine regulatory pathways.

The compound belongs to a class of melanocortin receptor agonists derived from the melanocyte-stimulating hormone (MSH) peptide family.

This preparation contains 10 mg of high purity lyophilized peptide supplied in a sealed research vial. The lyophilization process preserves peptide stability and allows researchers to reconstitute the compound for controlled in vitro experimentation.

Because of its defined peptide structure and stable analytical profile, PT-141 has become a widely referenced compound in experimental research models investigating melanocortin receptor signalling systems.

Compound Overview

PT-141 (Bremelanotide) is a synthetic cyclic peptide derived from analogues of alpha-melanocyte stimulating hormone (α-MSH).

Alpha-MSH peptides interact with melanocortin receptors, a group of G-protein coupled receptors involved in multiple physiological signalling pathways.

Research involving PT-141 commonly investigates its interaction with melanocortin receptor subtypes such as MC3R and MC4R.

Because of its well-defined receptor interaction profile, PT-141 is frequently used in experimental models exploring neuropeptide signalling, receptor activation mechanisms and peptide-mediated cellular communication.

Historical Background and Scientific Context

Scientific interest in melanocortin signalling systems increased significantly during the late twentieth century as researchers began mapping the role of melanocortin peptides in cellular communication and physiological regulation.

Alpha-melanocyte stimulating hormone and related peptides were identified as key signalling molecules interacting with melanocortin receptor systems.

As peptide synthesis technologies improved, researchers began developing synthetic analogues capable of selectively interacting with melanocortin receptors.

PT-141 emerged from this line of research as a synthetic melanocortin receptor agonist used in controlled laboratory models examining neuropeptide signalling pathways.

Mechanistic Focus in Research

Within experimental laboratory settings, PT-141 is commonly studied in relation to melanocortin receptor activation and neuropeptide signalling pathways.

Research investigations commonly explore the compound in experimental models examining:

• Melanocortin receptor signalling dynamics
• Neuropeptide receptor interaction pathways
• G-protein coupled receptor activation mechanisms
• Central signalling pathway modelling
• Comparative peptide receptor binding studies
• Molecular signalling cascade analysis
• Peptide-mediated cellular communication

These experimental models allow scientists to investigate molecular signalling mechanisms that regulate receptor activation and cellular communication networks.

Research Applications

In controlled research environments, PT-141 may be utilised in experimental models designed to explore melanocortin receptor signalling and neuropeptide regulatory systems.

Examples of research applications include:

• Melanocortin receptor signalling studies
• Neuropeptide pathway investigation
• Receptor interaction analysis
• Peptide signalling research
• Comparative receptor agonist evaluation
• Molecular regulatory pathway modelling
• Controlled in vitro peptide studies

Grail Formula Quality

Every Grail Formula research compound is produced under strict quality control procedures designed to support reliable laboratory experimentation.

Each batch undergoes independent analytical testing to verify:

• Compound identity
• Assay accuracy
• Purity confirmation
• Microbial safety
• Endotoxin levels
• Heavy metal screening
• Full batch traceability

All testing is performed by independent laboratories to ensure transparent verification and reproducible research material.

Research Use Limitation

• Used solely for in vitro experiments
• Not permitted for clinical trials involving humans
• Not permitted for human or veterinary administration
• Not permitted for investigational human use

Independently verified by Liquilabs s.r.o. (Czechia)
Validated assay content 11.88 mg
Confirmed purity 99 percent
Retention time and spectral identity confirmation
Endotoxin level 0.0120 EU per mg
No detectable microbial contamination
No detectable heavy metals
For research use only — not for human or veterinary use

For laboratory research only. Not intended for human consumption, injection, or cosmetic use.

This product is for research purposes only. Not for human use or diagnostic/therapeutic applications. Keep out of reach of children.